SS-31 50mg (Szeto-Schiller-31)

Form: Lyophilized Powder
Purity: >99%

Product Description

SS-31, also known as MTP-131 or Elamipretide, is a synthetic tetrapeptide specifically designed for research into mitochondrial dysfunction. Featuring a unique cationic 3+ charge at physiological pH, SS-31 efficiently permeates membranes and may cross the blood–brain barrier, making it a versatile tool for cellular and CNS research.

This peptide selectively localizes to the inner mitochondrial membrane and binds cardiolipin, a critical phospholipid for mitochondrial structure and function. By stabilizing cardiolipin and preventing oxidative inactivation by cytochrome c, SS-31 supports electron transport efficiency and reduces peroxidase activity. These actions collectively enhance ATP production while minimizing reactive oxygen species (ROS) leakage, a key factor in oxidative stress-related research.

Product Specifications

• Peptide Name: SS-31 (Szeto-Schiller-31)
• Concentration: 50mg per vial
• Purity: 99%+ HPLC & MS Verified
• Mechanism: Mitochondrial-targeting tetrapeptide (Cardiolipin binding)
• Format: Lyophilized Professional Grade Powder
• Storage: Store at -20°C for maximum stability and bio-activity

Core Research Focus Areas

1. Cardiolipin Protection: Investigate how SS-31 preserves cardiolipin and maintains mitochondrial cristae structure.
2. Electron Transport Efficiency: Study the peptide’s effects on cytochrome c activity to support ATP production and energy metabolism.
3. Oxidative Stress Reduction: Research its potential to reduce ROS leakage and protect cells from oxidative tissue injury.
4. CNS and Mitochondrial Delivery: Explore blood–brain barrier permeability for neuroprotective research.

Mechanism of Interest

• Cardiolipin Binding: Protects mitochondrial phospholipids from oxidative damage.
• Electron Transport Support: Promotes efficient electron transfer while reducing peroxidase activity.
• Oxidative Stress Reduction: Limits ROS formation and tissue oxidative injury.
• Blood–Brain Barrier Permeability: Enhanced CNS delivery due to cationic structure.

Molecular Information

• Molecular Formula: C32H49N9O5
• Molecular Weight: 639.8 g/mol
• Sequence: D-Arg–dimethylTyr–Lys–Phe–NH2
• Other Names: MTP-131, Elamipretide

Why Source from Bionex Peptides?

• America’s Premier Source: Highest-grade research materials for accurate and consistent laboratory protocols.
• HPLC Verified Quality: Every SS-31 50mg vial undergoes strict batch testing to ensure 99%+ purity.
• Rapid & Discreet Logistics: Fast, temperature-controlled, and secure shipping across the United States.

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  • Wiki / Reference: Sermorelin on Wikipedia